| dc.contributor.author |
Man, Adrian |
|
| dc.contributor.author |
Mare, Anca-Delia |
|
| dc.contributor.author |
Mareș, Mihai |
|
| dc.contributor.author |
Ruta, Florina |
|
| dc.contributor.author |
Pribac, Mirela |
|
| dc.contributor.author |
Maier, Adrian-Cornel |
|
| dc.contributor.author |
Cighir, Anca |
|
| dc.contributor.author |
Ciurea, Cristina-Nicoleta |
|
| dc.date.accessioned |
2024-06-17T07:08:11Z |
|
| dc.date.available |
2024-06-17T07:08:11Z |
|
| dc.date.issued |
2022-05-09 |
|
| dc.identifier.citation |
Man, Adrian, Anca-Delia Mare, Mihai Mares, Florina Ruta, Mirela Pribac, Adrian-Cornel Maier, Anca Cighir, and Cristina-Nicoleta Ciurea. 2022. “Antifungal and Anti-Virulence Activity of Six Essential Oils against Important Candida Species – a Preliminary Study.” Future Microbiology 17 (10): 737–53. https://doi.org/10.2217/fmb-2021-0296. |
en_US |
| dc.identifier.uri |
https://www.tandfonline.com/doi/full/10.2217/fmb-2021-0296 |
|
| dc.identifier.uri |
https://repository.iuls.ro/xmlui/handle/20.500.12811/4174 |
|
| dc.description.abstract |
Opportunistic infections with Candida species are becoming more problematic, considering their increasing virulence and resistance to antifungal drugs. Aim: To assess the antifungal and anti-virulence activity of basil, cinnamon, clove, melaleuca, oregano and thyme essential oils (EOs) on five Candida species (C. albicans, C. auris, C. krusei, C. parapsilosis and C. guillermondii). Methods: The MIC, growth rate, antibiofilm activity, regulation of gene expression (ALS3, SAP2, HSP70) and germ-tube formation were evaluated by specific methods. Results: Most EOs inhibited Candida species growth and reduced the expression of some virulence factors. Cinnamon and clove EO showed the most significant inhibitory effects. Conclusions: The tested EOs are promising agents for facilitating the management of some Candida infections. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
Taylor & Francis |
en_US |
| dc.rights |
Taylor & Francis |
|
| dc.subject |
antifungal activity |
en_US |
| dc.subject |
biofilm |
en_US |
| dc.subject |
Candida virulence |
en_US |
| dc.subject |
essential oils |
en_US |
| dc.subject |
gene regulation |
en_US |
| dc.title |
Antifungal and Anti-Virulence Activity of Six Essential Oils Against Important Candida Species – A Preliminary Study |
en_US |
| dc.type |
Article |
en_US |
| dc.author.affiliation |
Adrian Man, Anca-Delia Mare, Anca Cighir, Cristina-Nicoleta Ciurea, Department of Microbiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, Târgu Mureș, 540142, Romania |
|
| dc.author.affiliation |
Mihai Mares, Laboratory of Antimicrobial Chemotherapy, Ion Ionescu de la Brad University of Life Sciences of Iași, Iași, 700490, Romania |
|
| dc.author.affiliation |
Florina Ruta, Department of Community Nutrition & Food Safety, George Emil Palade University of Medicine, Pharmacy, Science, & Technology of Târgu Mureș, Târgu Mureș, 540142, Romania |
|
| dc.author.affiliation |
Mirela Pribac, Nutrition & Holistic Health, Holomed, Târgu Mureș, 540272, Romania |
|
| dc.author.affiliation |
Adrian-Cornel Maier, Department of Urology, 'Dunarea de Jos' University of Galați, Galați, 800008, Romania |
|
| dc.author.affiliation |
Anca Cighir, Cristina-Nicoleta Ciurea, Doctoral School, George Emil Palade University of Medicine, Pharmacy, Science, & Technology of Târgu Mureș, Târgu Mureș, 540142, Romania |
|
| dc.publicationName |
Future Microbiology |
|
| dc.volume |
17 |
|
| dc.issue |
10 |
|
| dc.publicationDate |
2022 |
|
| dc.startingPage |
737 |
|
| dc.endingPage |
753 |
|
| dc.identifier.eissn |
1746-0921 |
|
| dc.identifier.doi |
https://doi.org/10.2217/fmb-2021-0296 |
|