Abstract:
The investigations were based on determining influence of the variation of intestinal microflora to post vaccination antibody titers against Newcastle disease. Were formed 5 groups of one day old chickens which were vaccinated against Newcastle disease through different methods using vaccine strains La Sota and M5 clone30. Was collected the serum samples and samples of intestinal content for serological and microbiological tests to determine the titers level of antibodies and intestinal microflora composition and diversity. As a result it was determined that the variation of intestinal microflora is composed from cultures that are part of digestive tract in chickens (streptococci, bifid bacteria, Escherichia coli, and others) and post vaccine antibody titers obtained by experimental chickens groups was quite high in the groups which in ration was administered biomass of Streptomyces’s (23,8%)and increase the number of lymphocytes with 4.16% compared with control group of chickens. In same time haven’t been established a significant change in the composition of intestinal microflora of chickens.